On this page, you'll find updates on our research, initiatives and key findings that impact global health and pandemic science.

 We encourage you to visit regularly to stay informed about our work. For real-time updates and more in-depth insights, follow us on our social media channel!

Call for Working Group Proposals - Solicitation of Seed Ideas

NSF APPEX serves as a hub for multidisciplinary research to address the complexities of pandemic risk and response. We focus on the “what”, “how”, and “why” of expansion of disease outbreaks from local, isolated cases of infection into truly global threats. 

We are excited to announce our first semi-annual competition for new Seed Ideas for Working Groups - hearing from you what new and exciting thing APPEX should be working on next and recruiting new participants to form Working Groups around these seed ideas. This can be something you want to do yourself with our help or an idea you’ve always thought “someone should do”, even if you don’t want that someone to be you. If you have an exciting idea for how to study pandemic expansion, we want to work with you!

Our process for Working Group Proposals is a little different from what you might be used to at other Institutes and Centers, but we’re hoping it will be fun and easy - come take a look at the details here.

Our goal is to have completed discussion around these first-round seed suggestions by the end of February 2025. Please add your ideas and come back often to comment on/discuss ideas from others!



Coming Soon... Working Groups!

December 16, 2024

In January 2025, we will open our first call for seed ideas around which to
form new Working Groups!


What to propose: a question about what allows a disease to expand from a few cases
into an outbreak and then into a pandemic. The question should need input from
multiple disciplines to answer well. The strongest proposals will also have the potential
to translate basic research into real-world policy.
We’ll give each seed idea a platform and ask for community feedback and volunteers
who want to join a group working on this question (we’ll be using our Phase 1 piloted
GSOTP protocol). After community input, you’ll have a chance to revise the initial idea
and propose the team to our Selection Committee (first round decisions are planned by
March 1 st , 2025).


If your proposal is successful: Selected Working Groups will receive funds to meet in
person together, support from APPEX trainees (either a postdoc or graduate student) to
help advance the group’s efforts, and will have the option of requesting additional
resources (such as help from a research programmer, project management, publication
costs, etc.). Working Groups will also have support from experts in translational science
and policy impact to ensure the work they produce has the best chance of getting into
the hands of real-world decision makers who need it.
We’re so excited to hear your ideas and help you to build strong proposals for new
working groups to pursue them! Start thinking about what you’d want to do and check
back in early January for more details. Stay tuned!

White House Roundtable in Washington, D.C.

August 29, 2024

On August 27, 2024, Dr. Nina Fefferman, APPEX and NIMBioS Director and APPEX leadership team members, Dr. Sadie Ryan, Associate Director for Core and Working Group Research Efforts, and Dr. K. Selcuk Candan, Assoc. Director for Technology, Cyberinfrastructure and Tech Transfer, participated in the White House Roundtable on Emerging Technology for Preventing Health Emergencies in Washington, D.C.

We are proud that some of our APPEX team are being asked to influence national policy!

Official Launch of NSF APPEX!

August 22nd, 2024
We are thrilled to announce the launch of the United States National Science Foundation PIPP Phase 2 Center for Analysis and Prediction of Pandemic Expansion (NSF APPEX).

NSF APPEX will advance the ways in which pandemic scientists can understand how, why, and when the presence of an infection in a population will expand into endemic, epidemic, or pandemic disease rather than die out. Our goal is to identify the factors that constitute a “perfect storm” for pandemic expansion and explore ways humans can influence these factors to prevent and/or mitigate these threats. Using this framework, we will provide real-time response capabilities to identify the most sensitive, viable targets for intervention as new threats arise.

We are very grateful to the National Science Foundation (NSF) for their invaluable support. Their generous funding and trust have allowed us to make this exciting vision into a reality.

As we launch NSF APPEX, there will be so many opportunities to join us in working groups, workshops, tutorials, and more.

Please check our website regularly over the coming weeks to see how you might get involved! We are so excited for this new path and cannot wait to see the outcomes of our collaborations.

Connect with us 
on social media:

contact@appex.org
This material is based upon work supported by the National Science Foundation under Award No. 2412115. Any opinions, findings and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation